論文：COVID-19肺炎について放射線科医が知っておくべき必須事項

COVID-19の放射線科医にとっての必須事項：最新情報—放射線科学専門家パネル
ジェフリーP.カンネ、MD　放射線科　ウィスコンシン大学医学部公衆衛生学部

要約ポイント 
COVID-19感染患者の最大約50％が、COVID-19のインフルエンザ様症状の発症後0〜2日はCTスキャンが正常な場合があります。
COVID-19 RT-PCRの感度は、60〜70％と低い。したがって、COVID-19に起因する肺炎の患者は、胸部CTで肺の異常があっても、最初はRT-PCR陰性の場合がある。 
COVID-19感染の初期過程で、通常、約50％〜75％の患者で認める肺の異常は、両肺末梢の巣性または多巣性のすりガラス状の陰影です。 
病気が進行するにつれて、clazy-paving と consolidation がCTの主要な所見となり、ピークは9〜13日で、その後約1か月以上でゆっくりとクリアされます

Essentials for Radiologists on COVID-19: An Update—Radiology Scientific Expert Panel
Jeffrey P. Kanne, MD Department of Radiology University of Wisconsin School of Medicine and Public Health Madison WI

Summary Points
Up to approximately 50% of patients with COVID-19 infection may have normal CT scans 0–2 days after onset of flu-like symptoms from COVID-19
COVID-19 RT-PCR sensitivity may be as low as 60-70%; therefore patients with pneumonia due to COVID-19 may have lung abnormalities on chest CT but an initially negative RT-PCR
Lung abnormalities during the early course of COVID-19 infection usually are peripheral focal or multifocal ground-glass opacities affecting both lungs in approximately 50%–75% of patients.
As the disease progresses, crazy paving and consolidation become the dominant CT findings, peaking around 9–13 days followed by slow clearing at approximately 1 month and beyond.

JP Kanne, BP Little, JH Chung, BM Elicker, LH Ketai  Essentials for radiologists on COVID-19: an update—Radiology Scientific Expert Panel - Radiology, 2020